The Redskins lost two more players, Colt McCoy and Jordan Reed, to the Reserve/Injured list this week, but in a year dominated by the injury bug, more will impact Sunday's season finale against the Eagles.
Washington will be without tackle Ty Nsekhe (knee) and wide receiver Maurice Harris (concussion), as they have both been officially ruled out for the Week 17 contest.
"He was cleared to do a little bit of practice today, a little bit of work," Gruden said of Harris. "But then he still has follow up things that he has to do and we won't have time to get it all situated."
Tight end Vernon Davis is listed as doubtful with his own concussion, while several more are listed as questionable, including wide receiver Josh Doctson (illness), linebacker Ryan Anderson (hamstring), guard Tony Bergstrom (knee and ankle).
Davis missed last week's game against the Titans after experiencing concussion symptoms earlier in the week following the team's victory over the Jaguars.
Ioannidis has primarily dealt with a shin injury over the last several weeks but also injured his hamstring against the Titans. Anderson, dealing with his own hamstring injury, did play against the Titans last week after missing a couple games.
Bergstrom traveled with the team to Tennessee but was scratched before the game. With Nsekhe out, the Redskins would like to have him return to action one more time this season.