Jon Jansen remained limited in practice this week and was listed by the team as questionable for Sunday's game against the San Francisco 49ers.
Jansen has been slowed by a knee injury. He has missed the last two games as a result.
For the 49ers game, Jansen is expected to be a game time decision.
"If he can go, then he'll be our starter [at right tackle]," head coach Jim Zorn said.
Jason Fabini would start for the third week in a row if Jansen is unable to play.
Also, London Fletcher was held out of practice on Friday due to a lingering foot injury, but he was expected to play against the 49ers, Zorn said.
He was listed as questionable for the 49ers game.
Kedric Golston, still bothered by an ankle injury, was listed as questionable. He has missed two of the last three games due to the injury.
Even with the injuries, Zorn said that he would not play rookies on Sunday at the expense of winning the game.
"If it is within our plan of trying to win the game, then yes [rookies will be play]," Zorn said. "But we won't just experiment or give a guy a few reps because he is a young guy and we want to see him more.
"We are not going to get anything more out of that. We are going to get a lot more out of winning and that is what I want to do. I think everybody wants that as well."
-- CAMPBELL SCOUTS THE NINERS
In studying film of the 49ers, Jason Campbell has noticed that the 49ers have taken on the mentality of head coach Mike Singletary, the former hard-nosed Hall of Fame linebacker.
"When you look at their defense, they react to the ball very well," Campbell said. "They run to the football. Their corners are really good. Walt Harris played here, so I know Walt and his personality. I know Nate Clements is another guy who can make plays.
"Patrick Willis, a Pro Bowler, can run all over the field and make plays. Takeo Spikes is someone I know personally and you know he brings a motor to every game, every Sunday. It is definitely a tough challenge. They want nothing more than to end the season on a winning note, too."